Night blindness and conjunctival xerosis caused by vitamin A deficiency in patients with cystic fibrosis.

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چکیده

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Night blindness and conjunctival xerosis caused by vitamin A deficiency in patients with cystic fibrosis.

Forty three patients with cystic fibrosis, aged 8-44 years (median 16 years), were examined for evidence of vitamin A deficiency. Eight patients had abnormal dark adaptation tests and three had conjunctival xerosis. Serum vitamin A and retinol binding protein concentrations were significantly lower in the affected patients who were also more likely to have abnormal liver function tests. Five pa...

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Maternal Night Blindness: A New Indicator of Vitamin A Deficiency

N ight blindness—the inability to see after dusk or at night—is the most common ocular manifestation of moderate to severe vitamin A deficiency. Poor dark adaptation leading to night blindness occurs when there is decreased production of a vitamin A–dependent photosensitive pigment, rhodopsin, in the retinal receptors responsible for seeing under low levels of illumination (rods). Normally, whe...

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Vitamin D Deficiency in Cystic Fibrosis

Cystic Fibrosis is the most common inherited genetic respiratory disorder in the Western World. Hypovitaminosis D is almost universal in CF patients, likely due to a combination of inadequate absorption, impaired metabolism, and lack of sun exposure. Inadequate levels are associated with the high prevalence of bone disease or osteoporosis in CF patients, which is associated with increased morbi...

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The occurrence and effects of human vitamin E deficiency. A study in patients with cystic fibrosis.

The role of vitamin E in human nutrition was studied by investigation of patients with cystic fibrosis (CF) and associated pancreatic insufficiency. Vitamin E status was assessed by measurement of the plasma concentration of the principal circulating isomer, alpha-tocopherol. Results of such determinations in 52 CF patients with pancreatogenic steatorrhea revealed that all were deficient in the...

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Night Blindness and Diabetes in a Non-Caucasian Cystic Fibrosis Patient in Iran

Cystic fibrosis (CF) is an autosomal recessive lethal disease that is predominantly occur in the caucasian populations and causes many clinical signs. The major clinical signs are pancreatic insufficiency and progressive lung disease but night blindness and diabetes are less well known. We report a fifteen years old non-caucasian girl that have cystic fibrosis with atypical night blindness, dia...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1989

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.64.8.1151